Ledikast
Ledipasvir & Sofosbuvir Tablets
Ledikast
Composition: Ledipasvir & Sofosbuvir
Therapeutic Class: Direct-Acting Antivirals
Ledikast: Trusted Hepatitis C Medicine with Synergistic Power
Aprazer’s Ledikast is the widely prescribed and well-tolerated, scientifically backed formula against Hepatitis C infections.
Ledivakast, exported to 20+ countries, is widely accepted and preferred for consistent quality and efficacy.
Aprazer: Advancing Global Access to Hepatitis C Medicines
As the leading Hepatitis C medicine manufacturer and exporter, Aprazer develops affordable and high-quality hepatitis C medicines.
WHO-GMP certified, assured therapeutic efficacy and safety.
What is Ledikast?
Ledikast is a combination of two potent antivirals, used in Chronic Hepatitis C infections.
Uses of Ledikast
- • Used treatment for Hepatitis C in new patients
- • Used previously failed treatments
- • HIV-HCV co-infections
How does it work?
- • Ledipasivir – inhibit NS5A protein
- • Sofosbuvir – inhibits the NS5B polymerase enzyme
- • The combination offers a synergistic effect, inhibiting viral RNA replication and assembly.
Benefits
- • Can be used in compensated cirrhosis
- • HIV co-infections
- • In pediatric patients above 12 years of age
- • After liver transplants
- • Potent viral load suppression
- • Improves liver functions
Common Side Effects
- • Nausea
- • Dizziness
- • Headache
- • Digestive issues
- • Tiredness
- • Diarrhea
Serious Side Effects
- • Severe Bradycardia (when taken with amiodarone)
- • Hepatitis B flare-ups occur in previous hepatitis B infections.
- • Severe liver failure in an advanced stage of liver disorder
- • Severe drop in red blood count when combined with ribavirin
- • Changes in urination, swelling, and fatigue
- • Confusion, depression
Precautions
To be used cautiously in patients:
- • End-stage kidney disorder
- • Severe cirrhosis
- • HIV co-infections
- • Cardiac disorders
- • Drug interactions- amiodarone, ribavirin
- • Blood disorders
Contraindications
- • Not to be used if any previous allergy or hypersensitivity to Ledipasvir, sofosbuvir, or any excipients
- • Breastfeeding mothers
- • Pregnant women
Warning
- • It is a prescription drug to be taken under medical supervision only
Important Safety and Monitoring Information
Regular monitoring of hepatic functions, renal functions, cardiac functions, co-infections, blood count and neuropsychiatric adverse reactions.
Drug interactions – Ribavirin and Amiodarone
FAQ
Frequently Asked Questions
Why choose Ledikast for Ledipasvir/Sofosbuvir combination?
Ledikast tablets are affordable and of a global standard.
It is manufactured by Aprazer Healthcare.
Alcohol is unsafe with Ledikast (Ledipasvir & Sofosbuvir) therapy. Why?
It progresses liver disease.
Which tests must be done with Ledikast therapy?
- Hepatitis B screening
- hepatitis C screenings
- Liver functions
- Kidney functions
- Blood count
- Pregnancy status
Can Ledikast make you immune to passing the virus?
It cannot stop viral transmission.
In liver cirrhosis, can I use Ledikast?
It is safe to use.
It prevents disease progression.
Avoid medicines with Ledikast (Ledipasvir /Sofosbuvir). Which are they?
- Amiodarone
- Tubercular drugs
- Seizure drugs
Avoid Statins with Ledikast (Ledipasvir & Sofosbuvir) . Why?
Consult the doctor.
It can cause muscle breakdown.
Ledikast (Ledipasvir & Sofosbuvir) is safe in nursing women. How?
It is safely used.
It do not pass in milk.
Is Aprazer Healthcare known for Hepatitis medicines?
It is a hepatology drug manufacturer.
