Coliaxis
Colistimethate Sodium for Injection IP 1 Million IU
Coliaxis Injection
Composition – Colistimethate Sodium (1 Million IU)
Classification – Antibiotic Injection used in ICU
What is Coliaxis?
It is a very strong bactericidal, killing many bacteria and is used in severe infections. Coliaxis injection is used in ICUs for resistant bacterial infections.
Benefits of Coliaxis
- • Rapid bactericidal effect.
- • Used in multi-drug resistant infections.
- • Reduce severe endotoxin effects.
Uses of Coliaxis
- • Pneumonia induced by a ventilator
- • Sepsis (Infection in the blood)
- • Urinary Tract Infections
- • Infections of the brain (Meningitis)
How does Coliaxis work?
It leads to cell death by causing holes in the bacterial cell membrane.
The Common Side Effects of Coliaxis
- • Nausea
- • Vomiting
- • Cramps
- • Allergic reactions
- • Renal toxicity
- • Neurological toxicity
- • Visual disturbance
The Severe Side Effects of Coliaxis
- • Severe Renal toxicity
- • Neuromuscular blockade
- • Muscular paralysis
Precautions While Using Coliaxis
To be cautiously used in –
- • Renal disorders
- • Blood disorders
- • Severe illness
Important Considerations for Use
Due to its narrow therapeutic window, it requires careful dose monitoring.
Regularly monitor for –
- • Renal toxicity
- • Neurotoxicity
Contraindications
- • Allergy or hypersensitivity to drug components.
- • Myasthenia Gravis
Drug Interactions
- • Aminoglycosides
- • Other antibiotics
- • NSAIDS or other nephrotoxic drugs
- • Neuromuscular blocking drugs
- • General anesthetic drugs
Warning
To be used under a doctor or medical professional
Administration Instructions
- • It can be administered as IV, nebulization, or the intrathecal route.
Storage
- • Powdered form can be stored at room temperature.
- • The reconstituted solution can be stored at 2-8 degrees Celsius.
- • The reconstituted solution should be used within 24 hours.
Aprazer Healthcare- Affordable Critical Care Medicines
Aprazer Healthcare manufactures top–quality cephalosporin, penicillin, and polymyxin antibiotics, widely used in ICU care.
Why Aprazer Healthcare?
- • We are the leading critical care injection manufacturer and exporter, with remarkable global presence and worldwide availability, we are the leading pharmaceutical exporters.
- • Global Standard Medicines- WHO-GMP certified manufacturing facilities.
- • Assured Quality and Safety – Our stringent quality control measures ensure effective and safe formulations.
- • New Advanced Molecules – With high capital infrastructure, leveraging new technology, we are at the forefront in developing new drugs and innovative therapies.
FAQ
Frequently Asked Questions
Is Coliaxis (Colistimethate Sodium) a strong antibiotic?
It is used in severe infections.
- Pneumonia
- Urinary tract infection
- Infections due to cystic fibrosis
What are Coliaxis (Colistimethate Sodium) injection severe side effects?
- Nephrotoxicity
- Neurotoxicity
Is Coliaxis (Colistimethate Sodium) injection safe in a kidney disorder?
It should be used with extreme care__.
The dose should be reduced.
Kidney function must be monitored.
One must avoid driving after Coliaxis (Colistimethate Sodium) injection. Why?
It causes-
- Dizziness
- Slurred speech
- Vertigo
How long is Coliaxis (Colistimethate Sodium) solution stable?
The solution is kept at 2-8 degrees Celsius.
Discard after 7 days.
What happens in Coliaxis (Colistimethate Sodium) injection overdose?
- Acute renal insufficiency
- Respiratory paralysis
